beta propiolactone|BETA : Manila Beta-propiolactone (BPL) is the second most commonly used inactivation method for vaccine development after formaldehyde [23,26,42]. It is an alkylating agent that modifies the structure of nucleic acids forming crosslinks between DNA and proteins, and between DNA strands in the double helix ( Table 1 ) [ 52 ]. "Hey Timmy, you gonna eat that?" my friend, Chester, asked me pointing to my lunch. I shook my head. "Sweet!" Chester dove right in on eating my food. I guess since he wasn't able to afford his own food, he ate whatever he could, even garbage like that. "At least chew with your mouth closed," my other friend, AJ, said to Chester in disgust.
beta propiolactone,
β-Propiolactone, often simply called propiolactone, is an organic compound with the formula CH 2 CH 2 CO 2.It is a member of the lactone family, with a four-membered ring. It is a colorless liquid with a slightly sweet odor, highly soluble in water and organic solvents. [2] [3] The carcinogenicity of this compound has limited its commercial applications.[4]Beta-propiolactone is a colorless liquid with a strong, slightly sweet odor. It may occur naturally, but no clear documentation of its occurrence in nature was found, and it must be synthesized for commercial purposes.beta-Propiolactone can cause cancer according to an independent committee of scientific and health experts. California Office of Environmental Health Hazard Assessment (OEHHA) Beta-propiolactone appears as a colorless liquid with a slightly sweetish, pungent odor.Beta-propiolactone (BPL) is the second most commonly used inactivation method for vaccine development after formaldehyde [23,26,42]. It is an alkylating agent that modifies the structure of nucleic acids forming crosslinks between DNA and proteins, and between DNA strands in the double helix ( Table 1 ) [ 52 ].
BETA-PROPIOLACTONE is an ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by .
BPL, Hydroacrylic acid, β-lactone, 3-Hydroxy-β-lactone, 3-Hydroxy-propionic acid, β-Lactone, 2-Oxetanone, 3-Propiolactone Colorless liquid with a slightly sweet odor.BPL, Hydroacrylic acid, β-lactone, 3-Hydroxy-β-lactone, 3-Hydroxy-propionic acid, β-Lactone, 2-Oxetanone, 3-Propiolactone Colorless liquid with a slightly sweet odor.BETABPL, Hydroacrylic acid, β-lactone, 3-Hydroxy-β-lactone, 3-Hydroxy-propionic acid, β-Lactone, 2-Oxetanone, 3-Propiolactone Colorless liquid with a slightly sweet odor.beta propiolactone BETABPL, Hydroacrylic acid, β-lactone, 3-Hydroxy-β-lactone, 3-Hydroxy-propionic acid, β-Lactone, 2-Oxetanone, 3-Propiolactone Colorless liquid with a slightly sweet odor.beta-Propiolactone is used for vaccines, tissue grafts, surgical instruments, and enzymes, as a sterilant of blood plasma, water, milk, and nutrient broth, and as a vapor-phase disinfectant in enclosed spaces. Its sporicidal action is used against .
beta propiolactone β-Propiolactone is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals. β-Propiolactone caused tumors in two rodent species, at several different tissue sites, and by several different routes of exposure.
beta propiolactone|BETA
PH0 · β
PH1 · beta
PH2 · Propiolactone
PH3 · Methods of Inactivation of Highly Pathogenic Viruses for
PH4 · CDC
PH5 · Beta
PH6 · BETA